Some Recent Publications

Li, W., and Palmer, G., Spectroscopic characterization of the interaction of azide and thiocyanate with the binuclear center of cytochrome oxidase. Evidence for multiple ligand sites, Biochemistry 32, 1833-1843 (1993).

Day, E.P., Peterson, J., Sendova, M., Schoonover, J., and Palmer, G., Magnetization of fast and slow cytochrome c oxidase Biochemistry 32, 7855-7860 (1993).

Palmer, G., Current issues in the Chemistry of Cytochrome c Oxidase, J. Biomembranes BioEnergetics 25, 145-152 (1993).

Liao, G and Palmer, G. The reactionm of diamide and diimide with cytochrome oxidase FASEB J. 8, A1298 (1994).

Fabian, M. and Palmer, G. The Reaction of Cyanide with Peroxidatic Forms of Cytochrome Oxidase. Biochemistry 34 1534-1540 (1995).

Fabian, M and Palmer, G. The Interaction of Cytochrome Oxidase with Hydrogen Peroxide: The Relationship of P and F. Biochemistry 34 13802-13810 (1995).)

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    Guang-Ling Liao and Graham Palmer The Reduced minus Oxidized Difference Spectra of Cytochromes a and a3. Biochim Biophys Acta 1274 109-112 (1996)

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    James A. Fee, Donita Sanders,Claire E. Slutter,Peter E. Doan, Roland Aasa, Martin Karpefors, and Tore Yanngard. Multi-frequency epr evidence for a binuclear CuA center in cytochrome c oxidase: studies with a 63Cu- and 65 Cu-enriched soluble domain ofthe cytochrome ba3 subunit II from Thermus Thermophilus Biochem. Biophys. Res. Comm. 212 77-83 (1995).

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    Michael 1. Verkhovsky, Joel E. Morgan, and Marten Wikstrom. Control of Electron Delivery to the Oxygen Reduction Site of Cytochrome c Oxidase: A Role for Protons. Biochemistry 34 7483-7491 (1995)

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    Jose Castresana and Matti Saraste: Evolution of energetic metabolism: the respiration-early hypothesis TIBS Nov. 1995 443-448.

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    David M. Mitchell, Roland Aasa, Pia Adelroth, Peter Brezinski, Robert B. Gennis & Bo G. Malmstrom EPR studies of wildtype and several mutants of cytochrome c oxidase from Rhodobacter sphaeroides: Glu-286 is not a bridging ligand in the cytochrome a3CuB center. FEBS Lett. 374 371-374 (1995).

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    Yang C. Fann, Ishak Ahmed, Ninian J Blackburn, John S. Boswell, Marina L. Verkhovskaya, Brian M. Hoffman, and Marten Wikstrom. Structure of CuB in the Binuclear Heme—Copper Center of the Cytochrome aa3-Type Quinol Oxidase from Bacillus subtilis: An ENDOR and EXAFS Study. Biochemistry 34 10245-10255 (1995)

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    David M. Mitchell, Pia Adelroth, Jonathan P.Hosler, John R. Fetter, Peter Brzezinski, Michelle A. Pressler, Roland Aasa, Bo G. Malmstrom, James O. Alben, Gerald T. Babcock, Robert B. Gennis, and Shelagh Ferguson-Miller. A Ligand-Exchange Mechanism of Proton Pumpimg Involving Tyrosine-422 of Subunit I of Cytochrome Oxidase is Ruled Out. Biochemistry, 35 824-828(1996).

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    Claire E.Sutter, Ralf Langen, Donita Sanders, Stephen M. Lawrence, Pernilla Wittung, Angel J. Di Billio, Michael J. Hill, James A Fee, John H Richards, Jay Winkler and Bo G. Malmstrom. Electron-transfer studies with the CuA domain of Thermus thermophilus cytochrome ba3. Inorg Chim Acta243, 141-145(1996)

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    Joel E. Morgan, Michael T Verkovsky, Anne Puustinen, and Marten Wikstrom. Identification of a "Peroxy" Intermediate in Cytochrome b03 of Escherichia Coli. Biochemistry 1995, 34, 15633-15637

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    Jianling Wang, Jon Rumbley, Yuan-chin Ching, Satoshi Takahashi, Robert B. Gennis, and Denis L. Rousseau. Reaction of Cytochrome bo3 with Oxygen: Extra Redox Center(s) are Present in the Protein.Biochemistry 1995,34, 15504-15511.

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    Benjamin E. Ramirez, Bo G. Malmstrom, Jay R. Winkler and Harry B. Gray The currents of life: The terminal electron transfer complex of respiration

    Proc Natl Acad Sci 92. 11949-11951, 1995.

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    Matthias Wilmanns, Pekka Lappalainen, Mark Kelly, Elisabeth Sauer-Eriksson, and Matti Saraste.Crystal structure of the membrane-exposed domain from a respiratory quinol oxidase complex with an engineered dinuclear copper center. Proc. Natl. Acad. Sci. USA 92, 1955-11959, 1995.

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    Tatsushi Mogi, Tomoyasu Hirano, Hiro Nakamura, Yasuhiro Anraku, and Yutaka Orii. CuB promotes both binding and reduction of dioxygen at the heme-copper binuclear center in the Escherichia coli bo-type ubiquinol oxidase. FEBS Letters 370, 259-263, 1995.

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    C. Varotsis, G.T. Babcock, M. Lauraeus, and M. Wikström. Raman detection of a peroxy intermediate in the hydroquinone-oxidizing cytochrome aa3 of Bacillus subtilis. Biochim. Biophys. Acta 1231, 111-116, 1995.

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    David M. Mitchell & Robert B. GennisRapid purification of wildtype and mutant cytochrome c oxidasefrom Rhodobacter sphaeroides by Ni2+NTA affinity chromatography. FEBS Letters 368 (1995)148150

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    Robert P. Houser, Victor G. Young, Jr.,& William B. Tolman A Thiolate-Bridged, Fully Delocalized Mixed-Valence Dicopper(I,II) Complex that Models the CuA Biological Electron-Transfer Site. Journal of the American Chemical Society 1996, 118, 2101-2102.

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    Izaskun Echabe,Tuomas Haltia, Prnesto Freire, Felix M. Goni,1 and Jose Luis R. Subunit III of Cytochrome c Oxidase Influences the Conformation of Subunits I and II: An Infrared Study Biochemistry 1995, 84. 13565-13569

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    Michael Verkhovsky, Joel E. Morgan, Anne Puustinen & Marten Wikstrom Kinetic trapping of oxygen in cell respiration Nature 1996, 380, 268-270.

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    KaiTai Chang & Graham Palmer Formate Bound to Cytochrome Oxidase can be Removed by Cyanide and by Reduction. Biochim. Biophys Acta 1277 (1996) 237-242.

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    Denis A. Proshlyakov, Takashi Ogura, Kyoko Shinzawa-Itoh, Shinya Yoshikawa and Teizo Kitagawa Microcirculating System for Simultaneous Determination of Raman and Absorption Spectra of Enzymatic Reaction Intermediates and Its Application to the Reaction of Cytochrome c Oxidase with Hydrogen Peroxide Biochemistry, 1996, 35. 76-82

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    Martyn A. Sharpe, John M. Wrigglesworth, Jerome Louewen and Peter Nicholls Small pH Gradients Inhibit Cytochrome c Oxidase: Implications for H+ entry to the Binuclear Center Biochem. Biophys. Res Comm., 1995, 216. 931-938

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    Perrulla Wittung., Bo G. Malmstrom Redox linked conformational changes in cytochrome c oxidaseFEBS Letters 388 (1996) 47-49

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    Claire E. Slutter, Donita Sanders, Pernilla Wittung, Bo G. Malmstrom, Roland Aasa, John H. Richards, Harry B. Gray, and James A Fee. >Water-soluble, Recombinant CuA-Domain of the Cytochrome ba3 Subunit II from Thermus Thermophilus.Biochemistry 35 (1996) 3387-.

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    Tomitake Tsukihara, Hiroshi Aoyama, Eiki Yamashita, Takashi Tomizaki, Hiroshi Yamaguchi, Kyoko Shinzawa-ltoh, Ryosuke Nakashima, Rieko Yaono & Shinya Yoshikawa. The Whole Structure of the 13-Subunit Oxidized Cytochrome c Oxidase at 2.5 A. Science 272 (1996) 1136-1144.

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    Jaume Torres, Victor Darley-Usmar and Michael T. Wilson Inhibition of cytochrome c oxidase in turnover by nitric oxide: mechanism and implications for control of respiration Biochem. J.(1995) 312,(1995) 169–173

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    Vilmanté Borutaite and Guy C. Brown Rapid reduction of nitric oxide by mitochondria, and reversible inhibition of mitochondrial respiration by nitric oxide Biochem. J. 315, (1996) 295–299

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    Francesco Malatesta, Giovanni Antonini, Flavia Nicoletti, Alessandro Giuffre, Emilio d'Itri, Paolo Sarti and Maurizio Brunori Probing the high-affinity site of beef heart cytochrome c oxidase by cross-linking.. Biochem. J. 315,(1996)909–916.

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    Martyn A. Sharpe, John M. Wrigglesworth, Jerome Louewen and Peter Nicholls. Small pH Gradients Inhibit Cytochrome c Oxidase: Implications for H+ entry to the Binuclear CenterBiochem. Biophys. Res Comm. 216, 1995 931-938.

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    Sungjo Park, Lian-Ping Pan, Sunney I. Chan, and James O. Alben. Photoperturbation of the Heme a3-CuB Binuclear Center of Cytochrome c Oxidase CO Complex Observed by Fourier Transform Infrared Spectroscopy Biophysical Journal 71: 1036-1047, 1996.

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    Alessandro Giuffre, Paolo Sarti, Emilio D'Itri, Gerhard Buse, Tewfik Souliman and Maurizio Brunori On the Mechanism of Inhibition of Cytochrome c Oxidase by Nitric Oxide J. Biol Chem. 271: 33404-33408, 1996

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    Maurizio Brunori, Alessandro Giuffre, Emilio D'Itri and Paolo Sarti Internal Electron Transfer in Cu-Heme Oxidases: Thermodynamic or Kinetic Control? J. Biol Chem. in review (1997).

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    John Fetter, Martyn Sharpe, Jie Qian, Denise Mills, Shelagh Ferguson-Miller & Peter Nicholls Fatty Acids Stimulate & Restore Respiratory Control in a Proton Channel Mutant of Cytochrome Oxidase J. Biol Chem. in review (1997).

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    Jonathan P. Hosler, James P. Shapleigh, David C. Mitchell, Younkyoo Kim, Michelle Pressler, Christos Georgiou, Gerald T. Babcock, James O. Alben, Shelagh Ferguson-Miller and Robert B.Gennnis Polar residues in Helix VIII of Subunit I of Cytochrome c Oxidase Influence the Activity and the Structure of the Active Site Biochemistry 35 10776-10783 (1996).

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    Siegfried M. Musser, Yang-Cheng Fann, Ryszard J. Gurbiel, Brian M. Hoffman and Sunney I. Chan Q-band Electron Nuclear Double Resonance (ENDOR) and X-band EPR of the Sulfobetaine 12 heat-teated Cytochrome c Oxidase Complex J. Biol. Chem. 272 202-209 (1997) .

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    Artur Sucheta, Katy E. Georgiadis, and Olöf Einarsdottir Mechanism of Cytochrome c Oxidase-Catalyzed Reduction of Dioxygen to Water: Evidence for Peroxy and Ferryl Intermediates at Room Temperature Biochemistry 36: 554-565, 1997

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    Bruce Hill Stopped-Flow, Laser-Flash Photolysis Studies on the Reactions of CO and O2 with the Cytochrome caa3 Complex from Bacillus subtilis: Conservation of Electron Transfer Pathways from Cytochrome c to O2 Biochemistry 35: 6136-6143, 1996.

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    Peter Brzezinski Internal Electron Transfer Reactions in Cytochrome c Oxidase Biochemistry 35: 5611-5615, 1996.

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    Marian Fabian and Graham Palmer Hydrogen peroxide is not released following reaction of cyanide with several catalytically important derivatives of cytochrome c oxidase FEBS Lett. 422: 1-4, 1998.

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    Guang-Ling Liao and Graham Palmer Diazene-A Not-So-Innocent Ligand for the Binuclear Center of CYtochrome Oxidase Biochemistry in review 1998.

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