REFERENCES

• [1] Zou, G., and Phillips, G. N. Jr. A cellular automaton model for the regulatory behavior of muscle thin filaments. Biophys. J. 1994. 67, 11-28.

• [2] Toffoli, T. Physics and computation. International Journal of Theoretical Physics. 1982. 21, 165-174.

• [3] Hopcroft, J. E., and Ullman, J. D. Introduction to Automata Theory, Languages, and Computation. Addison-Wesley. Redwood City, CA. 1979.

• [4] Burks, A. W. Essays on Cellular Automata. Univ. of Illinois Press. Urbana, IL. 1970.

• [5] Wolfram, S. Cellular automata as models of complexity. Nature. 1984. 311, 419.

• [6] Hill, T. L., Eisenberg, E., and Greene, L. Theoretical model for the cooperative equilibrium binding of myosin subfragment 1 to the actin-troponin-tropomyosin complex. Proc. Natl. Acad. Sci. USA. 1980. 77, 3186-3190.

• [7] Hill, T. L. Two elementary models for the regulation of skeletal muscle contraction by calcium. Biophys. J. 1983. 44, 383-396.

• [8] Brandt, P. W., Cox, R. N., Kawai, M., and Robinson, T. Regulation of tension in skinned muscle fibers. J. Gen. Physiol. 1982. 79, 997-1016.

• [9] Brandt, P. W., Cox, R. N., and Kawai, M. Can the binding of to two regulatory sites on troponin C determine the steep pCa/tension relationship of skeletal muscle? Proc. Natl. Acad. Sci. USA. 1980. 77, 4717-4720.

• [10] McKillop, D. F. A., and Geeves, M. A. Regulation of the acto-myosin subfragment 1 interaction by troponin/tropomyosin. Biochem. J. 1991. 279, 711-718.

• [11] Tobacman, L. S., and Adelstein, R. S. Mechanism of regulation of cardiac actin-myosin subfragment 1 by troponin-tropomyosin. Biochemistry. 1986. 25, 798-802.

• [12] Phillips, G. N. Jr., Fillers, J. P., and Cohen, C. Tropomyosin crystal structure and muscle regulation. J. Mol. Biol. 1986. 192, 111-131.

• [13] Williams, Jr., D. L., Greene, L. E., and Eisenberg, E. Cooperative turning on of myosin subfragment 1 adenosinetriphosphatase activity by the troponin-tropomyosin-actin complex. Biochemistry. 1988. 27, 6987-6993.

• [14] Chalovich, J. Actin mediated regulation of muscle-contraction. Pharm. Thera. 1992. 55, 95-148.

• [15] Konishi, M., Wakabayashi, K., Kurihara, S., Higuchi, H., Onodera, N., Umazume, Y., Tanaka, H., Hamanaka, T., and Amemiya, Y. Time-resolved synchrotron X-ray diffraction studies of a single frog skeletal muscle fiber. Biophys. Chem. 1991. 39, 287-297.

• [16] Wyville, G., McPheeters, C., and Wyville, B. Data structures for soft objects in The Visual Computer. Springer International. 1986. pp.227-234.

• [17] Sillicon Graphics, Inc. Mountain View, Ca.

• [18] Orlova, A., and Egelman, E. H. A conformational change in the actin subunit can change the flexibility of the actin filament. J. Mol. Biol. 1993. 232, 334-341.

• [19] Orlova, A., Yu, X., and Egelman, E. H. Three-dimensional reconstruction of a co-complex of F-actin with antibody fab fragments to actin's terminus. Biophysical Journal. 1994. 66, 276-285.

• [20] Holmes, K. C., and Kabsch, W. Muscle proteins: actin. Current Opinion in Structural Biology. 1991. 1, 270-280.

• [21] Milligan, R. A., and Flicker, P. F. Structural relationships of actin, myosin, and tropomyosin revealed by cryo-electron microscopy. J. Cell Biol. 1987. 105, 29-39.

• [22] Rayment, I., Holden, H. M., Whitaker, M., Yohn, C. B., Lorenz, M., Holmes, K. C., and Milligan, R. A. Structure of the actin-myosin complex and its implications for muscle contraction. Science. 1993. 261, 58-65.

• [23] Winkelmann, D. A., Baker, T. S., and Rayment, I. Three-dimensional structure of myosin subfragment-1 from electron microscopy of sectioned crystals. J. Cell Biol. 1991. 114, 701-713.

• [24] Cohen, C., and Szent-Györgyi, A. G. J. Am. Chem. Soc. 1957. 79, 248.

• [25] Whitby, F. G., Kent, H., Stewart, M., Xie, X. Hatch, V., Cohen, C., and Phillips, G. N. Jr. Structure of tropomyosin at 9 Angstroms resolution. J. Mol. Biol. 1992. 227, 441-452.

• [26] Hitchcock, S., DeGregori, S. E. and Varnell, T. A. Tropomyosin has discrete actin-binding sites with sevenfold and fourteenfold periodicities. J. Mol. Biol. 1990. 214, 885-896.

• [27] Lehman, W., Craig, R., and Vibert, P. -induced tropomyosin movement in Limulus thin filaments revealed by three-dimensional reconstruction. Nature. 1994. 368, 65-67.

• [28] Flicker, P. F., Phillips, G. N. Jr., and Cohen, C. Troponin and its interactions with tropomyosin. J. Mol. Biol. 1982. 162, 495-501.

• [29] White, S. P., Cohen, C., and Phillips, G. N. Jr. Structure of co-crystals of tropomyosin and troponin. Nature. 1987. 325, 826-828.